Many scientific experiments generate large, multi-modal datasets, often in the form of time-series of different dimensionality. A particular challenge that scientists face in their workflows is comparing experiments to model and simulation, determining how close experiments match expected theory. The various analyses that scientists perform on these datasets can greatly be enhanced and accelerated by machine learning techniques, including recent deep learning and Bayesian inference techniques. The main objective of the workshop is to distill current machine learning techniques to a broad scientific audience at Princeton, and provide much needed research tools based on machine learning to advance their science. This should benefit mostly the Princeton research community but also the broader nearby research institutions.